8. 21c Museum Hotel, Louisville
Readers' Choice Rating: 96.3
Created from abandoned tobacco and bourbon warehouses, and doubling as a contemporary art museum with more than 9,000 square feet of exhibition space, this property has reclaimed-wood floors, hand-blocked linen upholstery, exposed brickwork and timber trusses, and glass transoms. "The art collection makes it such a fun place to stay." "Unique and creative" guest rooms have Herman Miller chairs, high ceilings, pewter mint julep cups, Malin and Goetz bath products, and rubber ducks in bathtubs. Proof on Main's menu is inspired by Italy and the American South, hence dishes like Marksbury Farm Bone-in Pork Chop or rye pasta carbonara, and a choice of more than 50 Kentucky bourbons, several bottled exclusively for the hotel. "It's an incredible place for such a small city."