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An Italian appeals court has rejected prosecutors’ request for new DNA testing in the Amanda Knox case. The forensic evidence that helped to convict the American student, including a knife that reportedly has Knox’s DNA on the handle, has been thrown into serious question by independent experts during the appeal trial, and without a clear motive for the crime it is a crucial piece of the case. The move is a boon to Knox’s defense, and it clears the way for closing arguments. A verdict is expected by the end of September.