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Rick Santorum needs to win Saturday's Louisiana primary, and it looks like he will as the state's voters head to the polls. The contest could rejuvenate his campaign and remind the GOP that frontrunner Mitt Romney lacks conservative support in the South, since Santorum won in Alabama and Mississippi also. But Romney already dealt a decisive loss to Santorum in Illinois on Tuesday, proving that he can win in big, industrial Midwestern states—despite the Etch a Sketch gaffes.