Christina Applegate Hospitalized for Weeks Amid Health Battle

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The actress was diagnosed with a chronic disease in 2021.

Christina Applegate in Los Angeles, California.
Gilbert Flores/Variety via Getty Images

Christina Applegate has been hospitalized in Los Angeles for several weeks, according to TMZ.

Sources close to the Dead to Me star, 54, reportedly said she was admitted in late March, though the exact reason for her stay remains unclear.

Applegate was diagnosed with multiple sclerosis, an autoimmune disease affecting the central nervous system, in 2021. It is an incurable condition that can cause vision issues, muscle weakness and stiffness, body tingling or numbness, clumsiness, and dizziness, among other symptoms.

Christina Applegate at the 75th Primetime Emmy Awards
Christina Applegate at the 75th Primetime Emmy Awards in Los Angeles, California, U.S. January 15, 2024. MARIO ANZUONI/REUTERS

The condition makes the actress prone to infection, and Applegate often requires emergency care, she revealed in her memoir You With The Sad Eyes, published in March.

Applegate’s rep declined to confirm whether the actress had been hospitalized, telling TMZ: “I have no comment whether she is in the hospital or what her medical treatments are.”

“She’s had a long history of complicated medical conditions that she has been refreshingly open about, as evidenced in her memoir and on her podcast,” her rep added.

On March 31, in an episode of Applegate’s podcast MeSsy, co-host Jamie-Lynn Sigler announced that the show would take a brief hiatus while both hosts were on book tours.

Applegate celebrated her memoir becoming the top The New York Times audiobook bestseller in March. “I can’t describe how much this means to me,” she said on Instagram on April 3.

In her memoir, she describes her daily struggles with her autoimmune condition.

“When I wake up, I often can’t get my arm to move far enough to grab the cup of water by my bed or my phone from its charger,” she wrote.

Christina Applegate
Applegate was diagnosed with multiple sclerosis in 2021. MARIO ANZUONI/REUTERS

The actress opened up about her struggles with multiple sclerosis in an interview with Good Morning America last month, telling co-anchor Robin Roberts that she hasn’t yet accepted her diagnosis.

“It still sucks, Robin. It really does,” Applegate said. “I have so many friends who have MS. And we talk to each other constantly. And I don’t have one that says, ‘I’m great.’”

“There is no great. There’s a better day and a less s---ty day,” she said. “This is a lifelong disease with no cure. Period.”

Applegate said it’s her daughter, whom she shares with her husband, Martyn LeNoble, that keeps her going.

“I wake up every day and go, ‘I’m Sadie’s momma.’ And that, to me, is why I’m still here,” Applegate added.

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