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Bayer AG has made an unsolicited bid to take over U.S. seed and pesticide giant Monsanto, which, if successful, would create an agriculture behemoth with annual revenue of more than $67 billion. Bayer said early Thursday the deal “would create a leading integrated agriculture business,” and Monsanto officials said its board was reviewing the bid. A statement called the offer “unsolicited” and “non-binding.” Even if Monsanto is interested, regulators may not be willing to bless the deal that would marry off the creator of aspirin to the inventor of the controversial herbicide Roundup.